New insights into the immunity and podocyte in glomerular health and disease: from pathogenesis to therapy in proteinuric kidney disease
PXM Rangel, A Priyadarshini… - Integrative Medicine in …, 2021 - journals.lww.com
Evidence has been furnished that immune cells, and immune-podocytes interactions have
increasingly become the focus of proteinuric kidney diseases, which affect millions of
patients worldwide. Podocytes are highly specialized, terminally differentiated epithelial
cells that wrap around the glomerulus to maintain the integrity of the glomerular filtration
barrier. More recent studies demonstrate that podocytes express many elements of the
innate and adaptive immune system including the complement components and receptors …
increasingly become the focus of proteinuric kidney diseases, which affect millions of
patients worldwide. Podocytes are highly specialized, terminally differentiated epithelial
cells that wrap around the glomerulus to maintain the integrity of the glomerular filtration
barrier. More recent studies demonstrate that podocytes express many elements of the
innate and adaptive immune system including the complement components and receptors …