[HTML][HTML] The dandelion dilemma revisited for oligoprogression: treat the whole lawn or weed selectively?
PH Patel, D Palma, F McDonald, AC Tree - Clinical Oncology, 2019 - Elsevier
Oligoprogressive disease is a relatively new clinical concept describing progression at only
a few sites of metastasis in patients with otherwise controlled widespread disease. In the era
of well-tolerated targeted treatments, resistance inevitably occurs and overcoming this is a
challenge. Local ablative therapy for oligoprogressive disease may allow the continuation of
systemic treatments by overcoming the few sub-clones that have developed resistance.
Stereotactic body radiotherapy is now frequently used in treating oligometastatic disease …
a few sites of metastasis in patients with otherwise controlled widespread disease. In the era
of well-tolerated targeted treatments, resistance inevitably occurs and overcoming this is a
challenge. Local ablative therapy for oligoprogressive disease may allow the continuation of
systemic treatments by overcoming the few sub-clones that have developed resistance.
Stereotactic body radiotherapy is now frequently used in treating oligometastatic disease …