Long-term follow-up on NRG oncology RTOG 0915 (NCCTG N0927): a randomized phase 2 study comparing 2 stereotactic body radiation therapy schedules for …

GM Videtic, R Paulus, AK Singh, JY Chang… - International Journal of …, 2019 - Elsevier
Purpose To present long-term results of RTOG 0915/NCCTG N0927, a randomized lung
stereotactic body radiation therapy trial of 34 Gy in 1 fraction versus 48 Gy in 4 fractions.
Methods and Materials This was a phase 2 multicenter study of patients with medically
inoperable non-small cell lung cancer with biopsy-proven peripheral T1 or T2 N0M0 tumors,
with 1-year toxicity rates as the primary endpoint and selected failure and survival outcomes
as secondary endpoints. The study opened in September 2009 and closed in March 2011 …