SLIT's prevention of the allergic march
F Porcaro, G Corsello, GB Pajno - Current allergy and asthma reports, 2018 - Springer
F Porcaro, G Corsello, GB Pajno
Current allergy and asthma reports, 2018•SpringerAbstract Purpose of Review The progression of atopic disorders from atopic dermatitis in
infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy
march. Allergen immunotherapy is the only causal treatment altering the immunological
mechanism underlying the allergic diseases. The sublingual administration route is more
acceptable than the subcutaneous one in pediatric age. Recent Findings Several studies
show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of …
infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy
march. Allergen immunotherapy is the only causal treatment altering the immunological
mechanism underlying the allergic diseases. The sublingual administration route is more
acceptable than the subcutaneous one in pediatric age. Recent Findings Several studies
show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of …
Purpose of Review
The progression of atopic disorders from atopic dermatitis in infants to allergic rhinitis and asthma in children, adolescents, and adults defines the allergy march. Allergen immunotherapy is the only causal treatment altering the immunological mechanism underlying the allergic diseases. The sublingual administration route is more acceptable than the subcutaneous one in pediatric age.
Recent Findings
Several studies show the efficacy and safety profile of sublingual immunotherapy (SLIT) for the treatment of respiratory allergy diseases, but few data are available on its effect of primary and secondary prevention of allergic disease.
Summary
The purpose of this manuscript is to review the latest studies addressing the effect of SLIT on the development of new sensitizations in not sensitized or already sensitized patients and progression of the allergy march.
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