Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study
Background Tocilizumab (TCZ), a humanized monoclonal antibody targeting the interleukin-
6 (IL-6) receptor, has been proposed for the treatment of COVID-19 patients; however,
limited data are available on the safety and efficacy. Methods We performed a retrospective
study on severe COVID-19 patients with hyper-inflammatory features admitted outside
intensive care units (ICUs). Patients treated with intravenous TCZ in addition to standard of
care were compared to patients treated with standard of care alone. Safety and efficacy were …
6 (IL-6) receptor, has been proposed for the treatment of COVID-19 patients; however,
limited data are available on the safety and efficacy. Methods We performed a retrospective
study on severe COVID-19 patients with hyper-inflammatory features admitted outside
intensive care units (ICUs). Patients treated with intravenous TCZ in addition to standard of
care were compared to patients treated with standard of care alone. Safety and efficacy were …