Intratubular large cell hyalinizing sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome
TM Ulbright, MB Amin, RH Young - The American journal of …, 2007 - journals.lww.com
We report the clinical and pathologic features of 8 boys with Peutz-Jeghers syndrome who
had distinctive testicular lesions. The patients were 4 to 13 years of age (mean, 6.5 y), and
all had gynecomastia, which was the presenting feature in 7. Physical examination
demonstrated bilateral testicular enlargement in the absence of a discrete mass. Advanced
bone age and elevated serum estradiol were demonstrated in 3 and 4 cases, respectively.
Testicular biopsy, performed in all cases, usually showed no gross abnormality, but on …
had distinctive testicular lesions. The patients were 4 to 13 years of age (mean, 6.5 y), and
all had gynecomastia, which was the presenting feature in 7. Physical examination
demonstrated bilateral testicular enlargement in the absence of a discrete mass. Advanced
bone age and elevated serum estradiol were demonstrated in 3 and 4 cases, respectively.
Testicular biopsy, performed in all cases, usually showed no gross abnormality, but on …
