Perspectives on testicular sex cord–stromal tumors and those composed of both germ cells and sex cord–stromal derivatives with a comparison to corresponding …
LM Roth, B Lyu, L Cheng - Human Pathology, 2017 - Elsevier
Sex cord–stromal tumors (SCSTs) are the second most frequent category of testicular
neoplasms, accounting for approximately 2% to 5% of cases. Both genetic and epigenetic
factors account for the differences in frequency and histologic composition between
testicular and ovarian SCSTs. For example, large cell calcifying Sertoli cell tumor and
intratubular large cell hyalinizing Sertoli cell neoplasia occur in the testis but have not been
described in the ovary. In this article, we discuss recently described diagnostic entities as …
neoplasms, accounting for approximately 2% to 5% of cases. Both genetic and epigenetic
factors account for the differences in frequency and histologic composition between
testicular and ovarian SCSTs. For example, large cell calcifying Sertoli cell tumor and
intratubular large cell hyalinizing Sertoli cell neoplasia occur in the testis but have not been
described in the ovary. In this article, we discuss recently described diagnostic entities as …