[HTML][HTML] In men at risk of HIV infection, IgM, IgG1, IgG3, and IgA reach the human foreskin epidermis
MP Lemos, ST Karuna, GJ Mize, Y Fong… - Mucosal …, 2016 - Elsevier
We profiled the humoral response in the penis, an area that has been minimally explored
but may be relevant for protecting insertive men against HIV and other sexually acquired
infections. Comparing paired tissue samples from 20 men at risk of HIV infection, foreskin
contains less immunoglobulin A (IgA) and more IgG2 than colon. Using foreskin dermal and
epidermal explants and paired plasma from 17 men, we examined Ig accumulation by
normalizing Ig to human serum albumin (HSA) transudation. Dermal IgM, IgG2, IgA, and IgE …
but may be relevant for protecting insertive men against HIV and other sexually acquired
infections. Comparing paired tissue samples from 20 men at risk of HIV infection, foreskin
contains less immunoglobulin A (IgA) and more IgG2 than colon. Using foreskin dermal and
epidermal explants and paired plasma from 17 men, we examined Ig accumulation by
normalizing Ig to human serum albumin (HSA) transudation. Dermal IgM, IgG2, IgA, and IgE …
