The lymphatic pathology of chronic Brugia pahangi infection in the dog
KF Snowden, B Hammerberg - Transactions of the Royal Society of …, 1989 - Elsevier
The dog infected with Brugia pahangi is an excellent model for studying the clinical and
immunological pathogenesis of lymphatic filarial infection and disease. Dogs demonstrated
a range of clinical changes including varying levels of microfilaraemia, episodic
lymphadenopathy, lymphangitis, and limb oedema similar to the clinical spectrum reported
in man. Histologically, tissues from parasite-infected dogs were characterized by fibrosis of
the lymph nodes and their afferent and efferent lymphatic ducts in the infected limbs. Some …
immunological pathogenesis of lymphatic filarial infection and disease. Dogs demonstrated
a range of clinical changes including varying levels of microfilaraemia, episodic
lymphadenopathy, lymphangitis, and limb oedema similar to the clinical spectrum reported
in man. Histologically, tissues from parasite-infected dogs were characterized by fibrosis of
the lymph nodes and their afferent and efferent lymphatic ducts in the infected limbs. Some …
