Inhibition of renin secretion by angiotensin. II.
AJ Vander, GW Geelhoed - Proceedings of the Society for …, 1965 - journals.sagepub.com
AJ Vander, GW Geelhoed
Proceedings of the Society for Experimental Biology and Medicine, 1965•journals.sagepub.comIntravenous infusion of angiotensin II (6.3-200 ng/kg min) inhibited renin secretion in dogs
under conditions of basal or elevated renin secretion. This inhibition was independent of
changes in mean renal arterial blood pressure. We propose a negative feedback effect of
circulating angiotensin on renin secretion.
under conditions of basal or elevated renin secretion. This inhibition was independent of
changes in mean renal arterial blood pressure. We propose a negative feedback effect of
circulating angiotensin on renin secretion.
Summary
Intravenous infusion of angiotensin II (6.3-200 ng/kg min) inhibited renin secretion in dogs under conditions of basal or elevated renin secretion. This inhibition was independent of changes in mean renal arterial blood pressure. We propose a negative feedback effect of circulating angiotensin on renin secretion.
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