The sFlt-1/PlGF ratio in different types of hypertensive pregnancy disorders and its prognostic potential in preeclamptic patients
S Verlohren, I Herraiz, O Lapaire, D Schlembach… - American journal of …, 2012 - Elsevier
OBJECTIVE: The soluble fms-like tyrosine kinase (sFlt-1)/placental growth factor (PlGF) ratio
is a reliable tool in the assessment of preeclampsia. We tested the hypothesis that the sFlt-
1/PlGF ratio is able to identify women at risk for imminent delivery. We characterized the sFlt-
1/PlGF ratio in different types of hypertensive pregnancy disorders. STUDY DESIGN: We
investigated 388 singleton pregnancies with normal pregnancy outcome, 164 with PE, 36
with gestational hypertension, and 42 with chronic hypertension. sFlt-1 and PlGF were …
is a reliable tool in the assessment of preeclampsia. We tested the hypothesis that the sFlt-
1/PlGF ratio is able to identify women at risk for imminent delivery. We characterized the sFlt-
1/PlGF ratio in different types of hypertensive pregnancy disorders. STUDY DESIGN: We
investigated 388 singleton pregnancies with normal pregnancy outcome, 164 with PE, 36
with gestational hypertension, and 42 with chronic hypertension. sFlt-1 and PlGF were …