[CITATION][C] Phosphorylation, allosteric effectors and inter-domain contacts in CAD; their role in regulation of early steps of pyrimidine biosynthesis
EA Carrey - Biochemical Society Transactions, 1993 - portlandpress.com
EA Carrey
Biochemical Society Transactions, 1993•portlandpress.comThe multienzyme polypeptide CAD comprises the following enzyme activities: glutamine-
dependent carbamyl phosphate synthetase (CPSase 11), aspartate transcarbamylase
(ATCase) and dihydroorotase (DHOase). The appropriate domains of the polypeptide thus
catalyse sequentially the first steps of pyrimidine biosynthesis in mammals. Figure 1
illustrates the concept of the molecule that we have
dependent carbamyl phosphate synthetase (CPSase 11), aspartate transcarbamylase
(ATCase) and dihydroorotase (DHOase). The appropriate domains of the polypeptide thus
catalyse sequentially the first steps of pyrimidine biosynthesis in mammals. Figure 1
illustrates the concept of the molecule that we have
The multienzyme polypeptide CAD comprises the following enzyme activities: glutamine-dependent carbamyl phosphate synthetase (CPSase 11), aspartate transcarbamylase (ATCase) and dihydroorotase (DHOase). The appropriate domains of the polypeptide thus catalyse sequentially the first steps of pyrimidine biosynthesis in mammals. Figure 1 illustrates the concept of the molecule that we have
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