Regulating B‐cell activation and survival in response to TLR signals
S Gerondakis, RJ Grumont… - Immunology and cell …, 2007 - Wiley Online Library
S Gerondakis, RJ Grumont, A Banerjee
Immunology and cell biology, 2007•Wiley Online LibraryFollowing encounters with microbes, cellular activation programs that involve the control of
proliferation and survival are initiated in follicular B cells either via the B‐cell receptor in a
specific antigen‐defined manner, or through Toll‐like receptors (TLRs) that recognize
specific microbial products. This review summarizes and discusses recent findings that shed
light on how the nuclear factor κB pathway controls and coordinates B‐cell division and
survival following TLR4 engagement.
proliferation and survival are initiated in follicular B cells either via the B‐cell receptor in a
specific antigen‐defined manner, or through Toll‐like receptors (TLRs) that recognize
specific microbial products. This review summarizes and discusses recent findings that shed
light on how the nuclear factor κB pathway controls and coordinates B‐cell division and
survival following TLR4 engagement.
Following encounters with microbes, cellular activation programs that involve the control of proliferation and survival are initiated in follicular B cells either via the B‐cell receptor in a specific antigen‐defined manner, or through Toll‐like receptors (TLRs) that recognize specific microbial products. This review summarizes and discusses recent findings that shed light on how the nuclear factor κB pathway controls and coordinates B‐cell division and survival following TLR4 engagement.
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