Assessment of vascular regeneration in the CNS using the mouse retina

K Miloudi, A Dejda, F Binet, E Lapalme… - JoVE (Journal of …, 2014 - jove.com
The rodent retina is perhaps the most accessible mammalian system in which to investigate
neurovascular interplay within the central nervous system (CNS). It is increasingly being
recognized that several neurodegenerative diseases such as Alzheimer's, multiple sclerosis,
and amyotrophic lateral sclerosis present elements of vascular compromise. In addition, the
most prominent causes of blindness in pediatric and working age populations (retinopathy of
prematurity and diabetic retinopathy, respectively) are characterized by vascular …