[HTML][HTML] Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
M Heverin, N Bogdanovic, D Lütjohann, T Bayer… - Journal of lipid …, 2004 - ASBMB
24S-hydroxycholesterol is a side-chain oxidized oxysterol formed in the brain that is
continuously crossing the blood-brain barrier to reach the circulation. There may be an
opposite flux of 27-hydroxycholesterol, which is formed to a lower extent in the brain than in
most other organs. Here we measured cholesterol, lathosterol, 24S-and 27-
hydroxycholesterol, and plant sterols in four different brain areas of deceased Alzheimer's
disease (AD) patients and controls. 24S-hydroxycholesterol was decreased and 27 …
continuously crossing the blood-brain barrier to reach the circulation. There may be an
opposite flux of 27-hydroxycholesterol, which is formed to a lower extent in the brain than in
most other organs. Here we measured cholesterol, lathosterol, 24S-and 27-
hydroxycholesterol, and plant sterols in four different brain areas of deceased Alzheimer's
disease (AD) patients and controls. 24S-hydroxycholesterol was decreased and 27 …
