Cloning of rat homologue of podocin: expression in proteinuric states and in developing glomeruli
H Kawachi, H Koike, H Kurihara, T Sakai… - Journal of the …, 2003 - journals.lww.com
Podocin is identified as a product of the gene mutated in a patient with autosomal recessive
steroid-resistant nephrotic syndrome. Although podocin is reported to be located at the slit
diaphragm area, the precise role of podocin for maintaining the barrier function of the slit
diaphragm has not been clearly elucidated. A rat homologue of podocin was cloned, and the
expression of podocin was investigated and then compared with the nephrin and the ZO-1
expressions in rat experimental proteinuric models and in developing glomeruli. Amino acid …
steroid-resistant nephrotic syndrome. Although podocin is reported to be located at the slit
diaphragm area, the precise role of podocin for maintaining the barrier function of the slit
diaphragm has not been clearly elucidated. A rat homologue of podocin was cloned, and the
expression of podocin was investigated and then compared with the nephrin and the ZO-1
expressions in rat experimental proteinuric models and in developing glomeruli. Amino acid …
