Superoxide dismutases and their impact upon human health
F Johnson, C Giulivi - Molecular aspects of medicine, 2005 - Elsevier
Superoxide dismutases (SOD), a group of metal-containing enzymes, have a vital anti-
oxidant role in human health, conferred by their scavenging of one of the reactive oxygen
species, superoxide anion. Three types of SODs are known in humans, with the most
abundant being cytosolic SOD1, identified by its Cu, Zn-containing prosthetic group. The
presence of these metals and the coordination to certain amino acids are essential for
function. SODs are among the first line of defense in the detoxification of products resulting …
oxidant role in human health, conferred by their scavenging of one of the reactive oxygen
species, superoxide anion. Three types of SODs are known in humans, with the most
abundant being cytosolic SOD1, identified by its Cu, Zn-containing prosthetic group. The
presence of these metals and the coordination to certain amino acids are essential for
function. SODs are among the first line of defense in the detoxification of products resulting …