[HTML][HTML] Expression of the serum-and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in …

MLL Leong, AC Maiyar, B Kim, BA O'Keeffe… - Journal of Biological …, 2003 - ASBMB
The effects of multiple stress stimuli on the cellular utilization of the serum-and glucocorticoid-
inducible protein kinase (Sgk) were examined in NMuMg mammary epithelial cells exposed
to hyperosmotic stress induced by the organic osmolyte sorbitol, heat shock, ultraviolet
irradiation, oxidative stress induced by hydrogen peroxide, or to dexamethasone, a synthetic
glucocorticoid that represents a general class of physiological stress hormones. Each of the
stress stimuli induced Sgk protein expression with differences in the kinetics and duration of …