Delayed puberty in girls with cystic fibrosis despite good clinical status

M Johannesson, C Gottlieb, L Hjelte - Pediatrics, 1997 - publications.aap.org
Background. Previous studies have shown that puberty is delayed among patients with
cystic fibrosis (CF). Malnutrition has been considered the main etiologic factor. Today with
improved medical therapy and nutritional support, most CF patients obtain an almost normal
nutritional status. Objectives. To investigate whether pubertal development among female
CF patients at the Stockholm CF Center was normal and, if not, what other parameters
besides nutrition might influence this. Methods. Seventeen patients were studied …