Predictors of survival in severe, early onset COPD
Study objectives: Multiple risk factors for mortality in patients with COPD have been
described, but most studies have involved older, primarily male subjects. The purpose of this
study was to determine the mortality rate and predictors of survival in subjects with severe,
early onset COPD. Design, setting, and participants: The cohort of 139 probands in the
Boston Early-Onset COPD Study was recruited from lung transplant and general pulmonary
clinics between September 1994 and July 2002. Subjects were< 53 years old, had an FEV 1 …
described, but most studies have involved older, primarily male subjects. The purpose of this
study was to determine the mortality rate and predictors of survival in subjects with severe,
early onset COPD. Design, setting, and participants: The cohort of 139 probands in the
Boston Early-Onset COPD Study was recruited from lung transplant and general pulmonary
clinics between September 1994 and July 2002. Subjects were< 53 years old, had an FEV 1 …
