Prostacyclin (PGI2) in pregnant human uterus
C Omini, GC Folco, R Pasargiklian, M Fano, F Berti - Prostaglandins, 1979 - Elsevier
Prostacyclin lowers the tonus and reduces the spontaneous motility of isolated pregnant
human myometrium. This effect seems to be related to cyclic-AMP accumulation, since PGI 2
increases the formation of this cyclic nucleotide in incubated minces of pregnant and non-
pregnant uterus. The ability of this tissue to generate a labile substance which inhibits
platelets aggregation, has been demostrated and discussed.
human myometrium. This effect seems to be related to cyclic-AMP accumulation, since PGI 2
increases the formation of this cyclic nucleotide in incubated minces of pregnant and non-
pregnant uterus. The ability of this tissue to generate a labile substance which inhibits
platelets aggregation, has been demostrated and discussed.
